One Thirty One Lameuse
Biloxi, MS
Downtown Biloxi's dressed-up New Orleans kitchen, tucked into a historic building on Lameuse Street — think duck poppers, seafood gumbo, and a balcony worth requesting.
Atmosphere
The dining room sits two stories up a staircase lined with old photographs of Biloxi, and that's your first clue this isn't a chain seafood house. Chef Lawrence Gautier built the place, by his own description, somewhere between a fish camp and a hunt club — exposed brick, warm lighting, a bar that turns out serious cocktails. Weather permitting, ask for the balcony; it looks down over Lameuse Street and is the best seat in downtown Biloxi on a mild evening. A singer working through 70s soft rock is a regular feature at weekend brunch, loud enough to notice, quiet enough that you can still talk. It reads upscale without tipping into stuffy.
What to Order
Start with the duck poppers — jalapeño and cream cheese wrapped around duck breast, bacon-wrapped and finished with a blackberry gastrique, the dish regulars mention before anything else. The charred oysters (parmesan or bacon-gouda) are worth ordering as a table snack while you decide on entrees. Seafood gumbo, built on a housemade shrimp stock with alligator sausage, stays on the menu year-round even as the rest rotates six to eight times a year. For dinner, the New Orleans BBQ shrimp and the Szechuan duck — peppercorn-marinated medallions over wild rice and Brussels sprouts — are standing favorites. At Sunday brunch, order the crab benedict or a mimosa flight and don't rush it.
Good to Know
One Thirty One Lameuse is closed Monday and Tuesday — those days are reserved for private events — and runs Wednesday through Friday for happy hour and dinner, with brunch and dinner both Saturday and Sunday. Reserve ahead through OpenTable, especially for weekend brunch, which fills up fast; a Sunday evening dinner is your best bet for a quieter table. Dress is business casual — nothing requires a jacket, but flip-flops and beach cover-ups feel out of place here. Parking is street and a public lot around downtown Biloxi, which can get tight during festival weekends. Expect to spend $30-50 a person before drinks. Families do bring kids, particularly to brunch, and the staff handles it well.
Our Take
This is the restaurant to book for a Biloxi date night or a milestone dinner, not a quick bite before the casino floor. The duck poppers and the gumbo earn their reputation, service is consistently praised, and the balcony table is genuinely worth requesting. Reviews do flag occasional slow kitchen stretches during a packed Saturday brunch, so build in some slack if you're on a schedule. Skip it if you want fast and casual — go on a Sunday evening instead, when it's calmer and the kitchen isn't underwater.
Details last verified August 2026. Always confirm current hours and menu directly with the restaurant.